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Sertraline (trade names Zoloft and others) is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. Sertraline is primarily prescribed for major depressive disorder in adult outpatients as well as obsessive-compulsive disorder, panic disorder, and social anxiety disorder, in both adults and children. Differences with other newer antidepressants are subtle and mostly confined to side effects.

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Tapering off Zoloft Including Lifestyle Changes and Alternative Therapies Community Q&A Zoloft, or sertraline, is an antidepressant in a class known as selective serotonin reuptake inhibitors (SSRIs).

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